Video Terms & Conditions - Waiver and Release of Liability All viewers of this video recognize and acknowledge that all content presented in this … Cyclobenzaprine has no effect on muscle function. Side effects include atropine-like responses and effects produced by inhibition of catecholamine uptake. Since cyclobenzaprine is so closely similar to amitriptyline in chemical structure, some of its effects are similar to the tricyclic antidepressants, including anticholinergic activity, potentiation of norepinephrine, and antagonism of reserpine. Cyclobenzaprine has not been shown to be effective in muscle spasm due to central nervous system disease. Cyclobenzaprine relieves muscle spasm when the spasm is due to local problems, that is, in the muscle itself and not in the nerves controlling the muscles. {{configCtrl2.info.metaDescription}} This site uses cookies.

Since cyclobenzaprine is so closely similar to amitriptyline in chemical structure, some of its effects are similar to the tricyclic antidepressants, including anticholinergic activity, potentiation of norepinephrine, and antagonism of reserpine. MECHANISM OF ACTION. Cyclobenzaprine and carisoprodol are muscle relaxants used for short-term relief of muscle spasms associated with acute painful muscle and skeletal conditions. Cyclobenzaprine relieves skeletal muscle spasm of local origin without interfering with muscle function. Skeletal muscle relaxant action: Cyclobenzaprine relaxes skeletal muscles through an unknown mechanism of action.

FLEXERIL (CYCLOBENZAPRINE HCl) Tablets DESCRIPTION Cyclobenzaprine hydrochloride is a white, crystalline tricyclic amine salt with the empirical formula C20H21N HCl and a molecular weight of 311.9. It has a melting point of 217ºC, and a pKa of 8.47 at 25ºC. Cyclobenzaprine hydrochloride is a white, crystalline tricyclic amine salt with the empirical formula C 20 H 21 N•HCl and a molecular weight of 311.9. PDF (1476 K) PDF-Plus (1534 K) Citing articles; Cyclobenzaprine: a possible mechanism of action for its muscle relaxant effect Mechanism Of Action.

It is freely soluble in water and alcohol, sparingly soluble in isopropanol, and insoluble in hydrocarbon solvents. It has a melting point of 217˚C, and a pK a of 8.47 at 25˚C. MECHANISM OF ACTION.

Cyclobenzaprine Hydrochloride is a centrally acting muscle relaxant, chemically similar to amitriptyline hydrochloride with antidepressant activity. A muscle relaxant is a drug that affects skeletal muscle function and decreases the muscle tone.It may be used to alleviate symptoms such as muscle spasms, pain, and hyperreflexia.The term "muscle relaxant" is used to refer to two major therapeutic groups: neuromuscular blockers and spasmolytics.Neuromuscular blockers act by interfering with transmission at the neuromuscular end … Cyclobenzaprine is a muscle relaxant. Cyclobenzaprine may act adversely with tramadol, antidepressants, meperidine, and MAO inhibitors.

The mechanism of action of cyclobenzaprine may be to increase brainstem-mediated noradrenergic inhibition of spinal cord neurons.

By continuing to browse this site you are agreeing to our use of cookies. Cyclobenzaprine seems to accomplish its beneficial effect through a complex mechanism within the nervous system, probably in the brainstem. Learn the dosage, side effects, and more about these medications. Cyclobenzaprine is a CNS depressant. The exact mechanism of action of cyclobenzaprine hydrochloride has not been fully determined.